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KOBE Life Science Cluster Company List

Business Expansion
on Kobe's Port Island



as of November 30, 2023

Companies are divided into categories by their major business field on Kobe Port Island. In the case they have other business fields, it is shown in the minor field.» List of KBIC companies(PDF)

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RD Dental Clinic

Major field:Hospitals

Miner field:Regenerative Medicine

RD Dental Clinic specializes in dental pulp regenerative therapy.


RD Dental Clinic specializes in the treatment for dental pulp regeneration. It also conducts research and development of new technologies for the advancement of dental pulp regenerative therapy. The dental pulp regenerative therapy is for teeth that had lost dental pulp due to deep caries. Autologous dental pulp stem cells (DPSCs) isolated from discarded teeth like wisdom teeth are transplanted into the teeth after root canal treatment and disinfection. This allows the pulp to be regenerated to the original state.

Product / Service / PR

    The important function of dental pulp is not only nutrition to the teeth but also reinnervation and revascularization. Pulp regenerative therapy is a promising approach for patients in a superaged society to maintain and prolong the function and endurance of teeth, which results in improvement in the quality of life.
Address: 1-3-1,Minatojimaminamimachi,Chuo-ku,Kobe, 650-0047  (Contact Person Mamiko Tsuji)
TEL: 078-304-5775 FAX: 078-304-5777
Web site: https://www.rdshikaclinic.com/ E-mail: info@rdshikaclinic.com

Rebirthel Co., Ltd.

Major field:Drug Discovery

Miner field:Regenerative Medicine

Miner field:Production of Drugs and Quasi Drugs


Rebirthel was founded in October 2019 with the aim of providing novel treatments against cancer, infectious diseases, and other immune-related diseases. Our strategy is based upon the technology of killer T cell regeneration from pluripotent stem cells, which was pioneered by Professor Hiroshi Kawamoto, Director of the Institute for Life and Medical Sciences, Kyoto University.
Rebirthel is one of the leading companies in the field of immunotherapy and has multiple globally patented technologies.

Product / Service / PR

    Rebirthel’s business consists of two main componets: i) in-house research, where we promote our own proprietary R&D and ii) licensing, where we license our technologies to other firms.
    Rebirthel’s in-house research has two priority pipeline projects: targeting WT1 antigens and regenerating tumor-infiltrating T lymphocytes.
    Regarding licensing, we have concluded research and commercial agreements with a variety of pharmaceutical companies.
Address: Room 311, Creation Core Kyoto Mikuruma, 448-5 Kajii-cho, Kamigyo-ku, Kyoto 602-0841 Japan  (Contact Person Masunori Kajikawa)
TEL: 075-212-3770 FAX: 075-212-3780
Web site: https://rebirthel.com/en E-mail: info@rebirthel.com


Major field:Regenerative Medicine

Miner field:Drug Discovery

Miner field:Cosmetic

Restore Vision Inc.

Major field:Drug Discovery

Miner field:Research Institutions, University and Academic Society, Foundation

Miner field:Hospitals

Developing a visual restoration gene therapy for retinitis pigmentosa


Restore Vision is a startup based in Japan aiming to develop a visual restoration gene therapy for retinitis pigmentosa. In collaboration with the Keio University School of Medicine, we have a promising product with high sensitivity enabling patients to see even under low light conditions. It has proven to have competitive advantages at the pre-clinical stage, and we are currently working towards an early clinical data acquisition.

Address: 15-1-3222 Tomihisa-cho, Shinjuku-ku, Tokyo, Japan 162-0067  (Contact Person Hikaru Miyazaki)
Web site: https://restore-vis.com/ E-mail: contact@restore-vis.com

RF Co., Ltd. (RF SYSTEM lab.)

Major field:Medical Equipment

Miner field:IT

Miner field:Outsourcing Business for Hospital

R&D of medical device softwares for x-ray computed tomography/digital radiography sensors


■Established: June, 1998 ■Headquarters: Nagano City, Nagano
■Capital: 1,782 million yen ■Employees: 350 (including the related companies)
Industrial: NDT X-Ray CT Scanner Systsems, Industrial Video Borescopes, Digital Radiography NDT Systems, etc.
Medical: X-Ray CT Scanners, Direct Digital Radiography Imaging Sensors, Medical Video Scopes, etc. / Capsule Endoscope and Disposable Video Endoscopes, etc.
Dental: CBCT, Intraoral / Panoramic and Cephalometric X-ray Digital X-ray Sensor, Intraoral Cameras, etc. / Okiraku Business (By RF929 Co., Ltd.)
■Branches (Direct Shops / Factories (Manufacturing facilities), Large commercial buildings, R&D centers, Training centers):
Asahikawa, Sapporo, Morioka, Ishinomaki, Tohoku, Omiya, Tokyo, Yokohama, Ngano Chuo (Central Research Laboratory), Nagano Tobu, Nagano Cone, Suzaka, Madarao, Matsumoto, Suwa, Niigata, Kanazawa, Hamamatsu, Nagoya, Kobe, Okayama, Miyoshi, Shikoku, Fukuoka, Kumamoto, Kagoshima

Product / Service / PR

    RF Co., Ltd is a research & development-oriented manufacturer, headquartered in Nagano. We are committed to "the production in purely domestic and domestic own factories" since its foundation and have been creating new products one after another with high-performance and low cost, with technological ideas and unique sense that can not be thought of from the conventional knowlege, keeping in our mind the motto of "the lower price nevertheless the better performance". Dental "NAOMI-CT" is our main products and we have obtained the top share just after 1 and half year after its release. We have seized No.1 share with NAOMi-CT and VJ in industrial, and NAOMI in medical market as well.
Address: 〈Tobu Manufacturing Facility〉
299-16 Minami Nagaike, Nagano City, Nagano, 381-0024 
〈Port Island Store〉
4-7-6 Minami Chou, Minatoshima, Chuou-Ku, Kobe City, Hyogo 650-0047 
(Contact Person Ms. Kobayashi, public relations)
TEL: +81-26-222-7760
FAX: +81-26-222-7719
Web site: http://www.rfsystemlab.com/en E-mail: hq@rfsystemlab.com


Major field:Research Institutions, University and Academic Society, Foundation

General Research Institute of natural sciences. The Kobe area revolves around life science and computational science research.


RIKEN was established in 1917 as the only research institute for natural science in Japan thanks to visionary financial support, which included the Imperial Household grant and contributions from industry and government. In April 2002, RIKEN Kobe campus opened as a research hub in the KOBE Biomedical Innovation Cluster promoted by Kobe city, and today, it is recognized as an international research base. More than 1,200 scientists and staff members work at the Kobe campus where joint research is conducted in collaboration with other medical institutions, research institutions and companies to solve various societal problems and shape the future of science.


RIKEN Center for Biosystems Dynamics Research (BDR)

The RIKEN Center for Biosystems Dynamics Research (BDR) seeks to identify mechanisms underlying the processes of development, growth, and aging from the molecular scale to the organism as a whole, with the goal of better understanding human health and disease, applying fundamental research outcomes in emerging fields such as regenerative medicine, in the hopes of helping to extend healthy lifespans.

  • ●Understanding the mechanisms behind the life cycle

    Laboratories at the BDR study the mechanisms underlying the generation and regeneration of tissues and organs in three dimensions, and behind the processes of aging and disease, with the ultimate goal of learning more about how a single fertilized egg is able to develop into a complex body capable of growth and maturation.

  • ● Understanding the mechanisms of molecules, cells and organs

    BDR scientists are working on imaging various molecules and cells with biological functions using a variety of techniques, including PET and MRI, with the goal of better understanding how molecules and cells interact within a highly interconnected organ system.

RIKEN Center for Computational Science (R-CCS)

The RIKEN Center for Computational Science (R-CCS) conducts research on high performance computing (HPC) & computational science, and on software development for practical applications. As the leadership center of HPC, researchers at R-CCS explore “the science of computing, the science by computing, and the science for computing.”

  • ● Development of the supercomputer Fugaku

    Development of the supercomputer Fugaku
    The supercomputer Fugaku, developed by RIKEN and Fujitsu, is planned to go into full operation around 2021. Fugaku will be used in a variety of areas such as drug discovery, prediction and mitigation of natural disasters, and industrial simulations. Fugaku will also become a platform for AI and big data research, fulfilling the needs of the society in the 21st century.

Integrated Innovation Building (IIB)

The Integrated Innovation Building (IIB) opened in 2015 as a RIKEN center to serve as a hub for collaboration between academia and industry. Since then, various industries have conducted collaborative research with RIKEN. RIKEN’s Interdisciplinary Theoretical and Mathematical Sciences Program (iTHEMS), which aims to shape the future of science through the study and application of mathematics, also uses IIB as its base in Kobe. Numerous seminars and events are held in the auditorium and other spaces, which are also available to outside users (a usage fee applies).

Address: 〒650-0047  2-2-3 Minatojima-minamimachi, Chuo-ku, Kobe, Hyogo, JAPAN  (Contact Person General Affairs Division)
TEL: +81-(0)78-306-0111 FAX: +81-(0)78-306-0101
Web site: https://www.riken.jp/en E-mail: kobe-soumu@riken.jp

RPM Co.,Ltd

Major field:CRO

Clinical development of pharmaceuticals and medical devices, contract business for post-marketing operations, pharmaceutical application support services, and temporary staffing/specialist recruiting.


As a contract research organization (CRO), we provide comprehensive support for clinical development, regulatory filings, and post-marketing activities for pharmaceuticals, medical devices, quasi-drugs, and in vitro diagnostic products. We support your business with both outsourced and temporary staffing services.

Product / Service / PR

    First-class marketing license for pharmaceuticals.
    (License No. 13A1X10130)
    Second-class marketing license for pharmaceuticals
    (License No. 13A2X10150)
    First-class marketing license for medical devices
    (License No. 13B1X10400)
    Marketing license for in-vitro diagnostics
    (License No. 13E1X00060)
Address: JRE Nishi-shinjuku Terrace, 3-2-4, Nishi-shinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan  (Contact Person Rurika Sato)
TEL: 03-5325-5800 FAX: 03-5325-5611
Web site: https://www.rpmedical.co.jp/ E-mail: r-sato@rpmedical.co.jp

RTC Co.,Ltd.Sensing & Electronics for Human & Machie

Major field:Medical Equipment

Miner field:Beauty and Health Care

Miner field:Production Equipment

We created the future for Medical Appliances, Care & Welfare and Medical Education by our exellent Electronical & Sensor Technology through development to manufacturing


(1)We do “Electronic Design and Manufacturing Service” and “Solution proposal for original Electronic Appliances” with our excellent technology, like design and development for electronic circuit, print circuit board, structure design, software and PCB assembly, complete manufacturing and evaluation in our in-house.
(2)We progress to develop the epoc making products with lots of Medical University and organaizetion as corabollation business.

Product / Service / PR

    We apply the above mentioned services for various electronic market as for medical, care nursing, welfare, rehabilitation and medical education.
    We have a long and deep experience in other market like automotive, industrial, consumer and so on, so we can propose these design philosophy to medical market.
    Our ultra-thin load sensor is applied to make data and
    visualize a condition that something something comes into contact.
    Our manufacturing plant is certified ISO13485.
Address: 3948, Kaminokawa, Kaminokawa-machi, Kawachi-gun, Tochigi-pref, 329-0611, Japan  (Contact Person Norinaga Sakurai)
TEL: 81-285-56-6213 FAX: 81-285-56-0197
Web site: http://www.rtc-corp.co.jp E-mail: norinaga_sakurai@rtc-corp.co.jp